Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 9/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786495 | 0.91 | PTGES (0.47) | PTGESHDAC2PRSS12HDAC1 | |
| SCHEMBL4786434 | 0.91 | PTGES (0.44) | PTGESCYP2D6CYP2C9PRSS12NPC1 | |
| SCHEMBL4784998 | 0.90 | PTGES (0.45) | PTGESHDAC2PRSS12HDAC1MAPK14 | |
| SCHEMBL4785770 | 0.87 | PTGES (0.42) | PTGESCYP2D6CYP2C9PRSS12MAPK14 | |
| SCHEMBL4785781 | 0.86 | PTGES (0.41) | PTGESCYP2D6CYP2C9PRSS12NPC1 | |
| SCHEMBL4786443 | 0.86 | PTGES (0.44) | PTGESPRSS12HDAC1MAPK14ALDH1A1 | |
| SCHEMBL4786085 | 0.86 | PTGES (0.41) | PTGESHDAC2CYP2D6CYP2C9PRSS12 | |
| SCHEMBL4787275 | 0.86 | PTGES (0.41) | PTGESCYP2D6CYP2C9PRSS12ALDH1A1 | |
| SCHEMBL4804034 | 0.85 | PTGES (0.40) | PTGESCYP2D6CYP2C9PRSS12ALDH1A1 | |
| SCHEMBL4786533 | 0.84 | PTGES (0.45) | PTGESPRSS12HDAC1MAPK14NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008084218-A1 | BENZAZOLE DERIVATIVES FOR THE TREATMENT OF INFLAMMATIONS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-07-17 | — | — | WO | disclosed |