Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14606948 | 0.80 | TSHR (0.41) | TSHRMTNR1AMTNR1BALDH1A1 | |
| SCHEMBL14606921 | 0.78 | TSHR (0.42) | TSHRFOLH1MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL5511756 | 0.76 | ARG1 (0.53) | TSHR | |
| SCHEMBL2757814 | 0.76 | ARG1 (0.53) | TSHR | |
| SCHEMBL8470091 | 0.76 | ARG1 (0.53) | TSHR | |
| SCHEMBL28709232 | 0.76 | CPB2 (0.36) | FOLH1ACE | |
| Hydrochloric Acid SCHEMBL5514291 | 0.75 | ARG1 (0.51) | TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL8469599 | 0.75 | ARG1 (0.51) | TSHRALDH1A1 | |
| SCHEMBL14607058 | 0.75 | TSHR (0.40) | TSHRMTNR1AMTNR1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL5514288 | 0.75 | ARG1 (0.51) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090434-A1 | SUBSTITUTED N-BICYCLICALKYL BICYCLIC CARBOXYAMIDE COMPOUNDS | PFIZER JAPAN INC. (JP) | 2008-07-31 | — | — | WO | disclosed |