Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237325 | 0.74 | SIGMAR1 (0.42) | SIGMAR1KDM4EALDH1A1GRIN2BMEN1 | |
| SCHEMBL4240896 | 0.73 | SIGMAR1 (0.40) | SIGMAR1KDM4EALDH1A1GRIN2BMEN1 | |
| SCHEMBL4248310 | 0.73 | SIGMAR1 (0.40) | SIGMAR1KDM4EGRIN2BL3MBTL1MEN1 | |
| SCHEMBL4246890 | 0.72 | SIGMAR1 (0.43) | SIGMAR1KDM4EALDH1A1GRIN2BL3MBTL1 | |
| SCHEMBL4786760 | 0.72 | CHRM2 (0.52) | SIGMAR1OPRM1GRIN2BMEN1KMT2A | |
| SCHEMBL4241897 | 0.72 | CHRM2 (0.45) | SIGMAR1OPRM1GRIN2BL3MBTL1 | |
| SCHEMBL4238217 | 0.71 | HTT (0.45) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL4245846 | 0.71 | MEN1 (0.40) | SIGMAR1KDM4EALDH1A1GRIN2BMEN1 | |
| SCHEMBL4249836 | 0.70 | GRIN2B (0.40) | SIGMAR1GRIN2B | |
| SCHEMBL4237318 | 0.70 | SIGMAR1 (0.44) | SIGMAR1GRIN2BMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |