Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4237510 | 0.89 | MEN1 (0.41) | MEN1KMT2ASIGMAR1S1PR4S1PR1 | |
| SCHEMBL4246890 | 0.88 | SIGMAR1 (0.43) | SIGMAR1S1PR5ACHEKDM4EALDH1A1 | |
| SCHEMBL4248310 | 0.86 | SIGMAR1 (0.40) | MEN1KMT2ASIGMAR1ACHEKDM4E | |
| SCHEMBL4237283 | 0.79 | SIGMAR1 (0.42) | MEN1KMT2ASIGMAR1NR1H4S1PR4 | |
| SCHEMBL4244829 | 0.77 | SIGMAR1 (0.41) | MEN1KMT2ASIGMAR1ACHEGRIN2B | |
| SCHEMBL4237268 | 0.76 | MEN1 (0.42) | MEN1KMT2ASIGMAR1NR1H4S1PR4 | |
| SCHEMBL4244909 | 0.75 | S1PR1 (0.44) | MEN1KMT2ASIGMAR1S1PR4S1PR1 | |
| SCHEMBL4245844 | 0.75 | ACHE (0.48) | MEN1KMT2ASIGMAR1NR1H4KCNH2 | |
| SCHEMBL4237271 | 0.75 | CHRM2 (0.46) | MEN1KMT2ANR1H4PTGESALOX5 | |
| SCHEMBL4786764 | 0.71 | SIGMAR1 (0.43) | MEN1KMT2ASIGMAR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012116-A1 | Muscarinic Receptor Antagonists | RANBAXY LABORATORIES LIMITED (IN) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012116-A1 | Muscarinic Receptor Antagonists | CHRM3, CHRM2, CHRM5 | MEN1 1950/4885KMT2A 2913/4885SIGMAR1 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.