Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 3/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784128 | 0.90 | EPHX1 (0.47) | EPHX1KDREPHX2HDAC1HDAC2 | |
| SCHEMBL4228945 | 0.84 | HRH3 (0.43) | QPCTHRH3KDRMAPTHSD17B10 | |
| SCHEMBL4787430 | 0.83 | EPHX2 (0.54) | EPHX1EPHX2 | |
| SCHEMBL4785572 | 0.81 | EPHX1 (0.51) | EPHX1KDREPHX2HDAC1HDAC2 | |
| SCHEMBL4787668 | 0.80 | MAPT (0.51) | EPHX1KDREPHX2HDAC1HDAC2 | |
| SCHEMBL4686265 | 0.79 | EPHX1 (0.46) | EPHX1KDREPHX2HDAC1HDAC2 | |
| SCHEMBL4683265 | 0.78 | EPHX1 (0.46) | EPHX1KDREPHX2MAPT | |
| SCHEMBL4787476 | 0.77 | EPHX1 (0.52) | EPHX1KDREPHX2HDAC1HDAC2 | |
| SCHEMBL4687172 | 0.77 | CCR3 (0.46) | QPCTHRH3KDRMAPT | |
| SCHEMBL4787105 | 0.76 | EPHX1 (0.52) | EPHX1KDREPHX2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |