Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688997 | 0.89 | EPHX2 (0.55) | EPHX1KMT2AEPHX2RAB9ANPC1 | |
| SCHEMBL4784128 | 0.87 | EPHX1 (0.47) | EPHX1KMT2AEPHX2MAPTSMN1; SMN2 | |
| SCHEMBL4686265 | 0.85 | EPHX1 (0.46) | EPHX1KMT2AEPHX2ALDH1A1HTT | |
| SCHEMBL4683259 | 0.84 | PKM (0.49) | KMT2ARAB9AMAPTNPC1PKM | |
| SCHEMBL4787476 | 0.81 | EPHX1 (0.52) | EPHX1KMT2AEPHX2MAPTALDH1A1 | |
| SCHEMBL4787221 | 0.81 | EPHX1 (0.52) | EPHX1KMT2AEPHX2MAPTALDH1A1 | |
| SCHEMBL4786697 | 0.80 | EPHX1 (0.48) | EPHX1KMT2AEPHX2ALDH1A1HTT | |
| SCHEMBL4682919 | 0.79 | HDAC1 (0.51) | EPHX1KMT2AEPHX2RAB9AMAPT | |
| SCHEMBL5149857 | 0.79 | KDR (0.56) | EPHX1KMT2AEPHX2MAPTPKM | |
| SCHEMBL4683716 | 0.79 | KDR (0.56) | EPHX1KMT2AEPHX2MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |