Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | GHSR | Q92847 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784128 | 0.87 | EPHX1 (0.47) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL4787430 | 0.87 | EPHX2 (0.54) | EPHX1EPHX2KMT2AMEN1 | |
| SCHEMBL4786348 | 0.85 | KDR (0.55) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL4787089 | 0.84 | EPHX1 (0.61) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL12362189 | 0.83 | EPHX1 (0.65) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL4783711 | 0.82 | EPHX2 (0.55) | EPHX1ALDH1A1HTTEPHX2KDR | |
| SCHEMBL4786985 | 0.81 | QPCT (0.46) | EPHX1HDAC1HDAC2EPHX2KDR | |
| SCHEMBL4787105 | 0.80 | EPHX1 (0.52) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL4689241 | 0.80 | HDAC1 (0.64) | EPHX1ALDH1A1HTTHDAC1HDAC2 | |
| SCHEMBL7197441 | 0.79 | EPHX1 (0.63) | EPHX1ALDH1A1HTTHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |