Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787612 | 0.80 | NPC1 (0.47) | ELANEKMT2AHPGDNPC1RAB9A | |
| SCHEMBL4787096 | 0.69 | KMT2A (0.39) | ELANEKMT2AHPGDKDM4ELMNA | |
| SCHEMBL4215088 | 0.66 | TP53 (0.46) | ELANEKMT2AHPGDHSD17B10ALDH1A1 | |
| SCHEMBL2304978 | 0.65 | TYRO3 (0.48) | ELANELMNAPDGFRACDK5TYRO3 | |
| SCHEMBL23115813 | 0.64 | SMN1; SMN2 (0.45) | KMT2AKDM4ELMNAMAPTALDH1A1 | |
| SCHEMBL4785235 | 0.63 | CREBBP (0.52) | ELANEKMT2AHPGDLMNAMAPT | |
| SCHEMBL30457321 | 0.63 | CHEK1 (0.67) | ELANEKMT2AHPGDKDM4EHSD17B10 | |
| SCHEMBL2356995 | 0.63 | TYRO3 (0.46) | ELANELMNAPDGFRACDK5TYRO3 | |
| SCHEMBL19249086 | 0.63 | ELANE (0.39) | ELANEKMT2ANPC1RAB9A | |
| SCHEMBL15110983 | 0.62 | KDM4E (0.34) | KMT2AHPGDKDM4EMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110863-A1 | INDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-09-18 | — | — | WO | disclosed |