Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 10/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4215088 | 0.81 | TP53 (0.46) | NPC1RAB9ATP53ELANEKMT2A | |
| SCHEMBL4787110 | 0.80 | ELANE (0.35) | NPC1RAB9ATP53ELANEKMT2A | |
| SCHEMBL28337035 | 0.74 | ELANE (0.50) | NPC1RAB9AELANEKMT2AMEN1 | |
| SCHEMBL4748268 | 0.73 | ELANE (0.40) | ELANEKMT2AMEN1HPGD | |
| SCHEMBL1141403 | 0.73 | NPC1 (0.57) | NPC1RAB9ATP53ELANEKMT2A | |
| SCHEMBL1981917 | 0.72 | TP53 (0.44) | NPC1RAB9ATP53ELANEKMT2A | |
| SCHEMBL5120623 | 0.72 | HSD17B10 (0.56) | NPC1RAB9AELANEKMT2AHPGD | |
| SCHEMBL4454198 | 0.71 | NPC1 (0.42) | NPC1RAB9ATP53ELANEKMT2A | |
| SCHEMBL1161440 | 0.70 | NPC1 (0.49) | NPC1RAB9ATP53KMT2AMEN1 | |
| SCHEMBL1855369 | 0.69 | SCN9A (0.45) | NPC1RAB9ATP53ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110863-A1 | INDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | GLENMARK PHARMACEUTICALS S.A. (US) | 2008-09-18 | — | — | WO | disclosed |