Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785583 | 0.94 | EPHX1 (0.49) | EPHX1S1PR1SLC6A3EPHX2ALDH1A1 | |
| SCHEMBL4682559 | 0.90 | SLC6A3 (0.51) | EPHX1S1PR1SLC6A3EPHX2RAF1 | |
| SCHEMBL4787105 | 0.86 | EPHX1 (0.52) | EPHX1EPHX2ALDH1A1HTTMEN1 | |
| SCHEMBL4788499 | 0.86 | TBXA2R (0.54) | EPHX1MEN1KMT2A | |
| SCHEMBL4785993 | 0.85 | EPHX1 (0.53) | EPHX1EPHX2ALDH1A1HTTKDR | |
| SCHEMBL4787348 | 0.85 | EPHX2 (0.55) | EPHX1EPHX2ALDH1A1HTTKDR | |
| SCHEMBL4786099 | 0.84 | EPHX1 (0.52) | EPHX1EPHX2ALDH1A1HTTMEN1 | |
| SCHEMBL5149417 | 0.84 | EPHX1 (0.52) | EPHX1EPHX2ALDH1A1HTTKMT2A | |
| SCHEMBL4786912 | 0.84 | KDR (0.54) | EPHX1EPHX2ALDH1A1HTTMEN1 | |
| SCHEMBL4783970 | 0.84 | EPHX2 (0.60) | EPHX1EPHX2ALDH1A1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |