Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784488 | 0.92 | EPHX2 (0.48) | EPHX2TBXA2RKMT2ALMNAKDR | |
| SCHEMBL4787266 | 0.90 | EPHX2 (0.51) | EPHX2TBXA2RLMNAMAPTEPHX1 | |
| SCHEMBL4785116 | 0.86 | TBXA2R (0.58) | EPHX2TBXA2RPOLB | |
| SCHEMBL4783711 | 0.85 | EPHX2 (0.55) | EPHX2TBXA2RLMNAMAPTRAB9A | |
| SCHEMBL4788372 | 0.84 | LMNA (0.44) | EPHX2KMT2ALMNAKDRALDH1A1 | |
| SCHEMBL4229012 | 0.83 | PKM (0.50) | KMT2ANPC1MAPTPKMRAB9A | |
| SCHEMBL4787476 | 0.83 | EPHX1 (0.52) | EPHX2TBXA2RKMT2AMAPTEPHX1 | |
| SCHEMBL4687617 | 0.82 | EPHX2 (0.47) | EPHX2TBXA2RKMT2AMAPTKDR | |
| SCHEMBL4787105 | 0.81 | EPHX1 (0.52) | EPHX2TBXA2RKMT2ASMN1; SMN2EPHX1 | |
| SCHEMBL4687220 | 0.80 | EPHX2 (0.49) | EPHX2TBXA2RLMNANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |