Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM5C | P41229 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787354 | 0.79 | FOLH1 (0.40) | FOLH1ECE1HDAC7HDAC8HDAC6 | |
| SCHEMBL14667663 | 0.79 | SMN1; SMN2 (0.55) | SMN1; SMN2SLC22A6GABRR1LMNATDP1 | |
| SCHEMBL6412296 | 0.77 | ECE1 (0.42) | FOLH1LMNAECE1HDAC7HDAC8 | |
| SCHEMBL11414379 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2SLC22A6GABRR1LMNATDP1 | |
| SCHEMBL27261261 | 0.73 | SMN1; SMN2 (0.48) | SMN1; SMN2SLC22A6GABRR1LMNATDP1 | |
| SCHEMBL27578968 | 0.72 | TSHR (0.46) | SLC22A6FOLH1LMNAECE1TDP1 | |
| SCHEMBL1419558 | 0.72 | FOLH1 (0.41) | SLC22A6FOLH1GABRR1LMNAECE1 | |
| Malic Acid SCHEMBL256122 | 0.71 | — | — | |
| Malic Acid SCHEMBL89131 | 0.71 | SMN1; SMN2 (1.00) | SMN1; SMN2SLC22A6GABRR1LMNATDP1 | |
| Malic Acid SCHEMBL31673494 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119028-A1 | ALKENYLDIARYLMETHANES HAVING NITROGEN-CONTAINING CARBOXYLIC ACID DERIVATIVES | CUSHMAN MARK S (US) | 2008-10-02 | — | — | WO | claimed |
| US-5733342-A | BUILDERS AND BLEACH STABILIZERS IN DETERGENTS AND CLEANING COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-03-31 | — | — | US | disclosed |