Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650919 | 0.70 | BAZ2B (0.46) | BAZ2BRAB9ANPC1KDM4EGAA | |
| SCHEMBL17051152 | 0.70 | BAZ2B (0.53) | BAZ2BRAB9ANPC1KDM4EGAA | |
| SCHEMBL357627 | 0.70 | BAZ2B (0.63) | BAZ2BRAB9ANPC1KDM4EGAA | |
| SCHEMBL26847564 | 0.69 | ALDH1A1 (0.38) | BAZ2BRAB9AMAPTNPC1POLB | |
| SCHEMBL27787704 | 0.67 | BAZ2B (0.66) | BAZ2BRAB9ANPC1KDM4EGAA | |
| SCHEMBL15761273 | 0.67 | BAZ2B (0.50) | BAZ2BRAB9AMAPTNPC1KDM4E | |
| SCHEMBL17134054 | 0.67 | BAZ2B (0.50) | BAZ2BRAB9AMAPTNPC1KDM4E | |
| SCHEMBL19143370 | 0.66 | BAZ2B (0.53) | BAZ2BRAB9ANPC1KDM4EGAA | |
| SCHEMBL222289 | 0.66 | BAZ2B (0.63) | BAZ2BRAB9ANPC1POLBKDM4E | |
| SCHEMBL4787405 | 0.66 | BCHE (0.41) | RAB9AMAPTNPC1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098859-A1 | HCV POLYMERASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-21 | — | — | WO | disclosed |