Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 9/20 | 0.54 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576853 | 0.83 | HPGD (0.56) | HRH4KDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL29063260 | 0.82 | HRH4 (0.40) | HRH4MAP2K1KDM4EPDPK1ALDH1A1 | |
| SCHEMBL16571364 | 0.82 | MAP2K1 (0.50) | HRH4MAP2K1KDM4EPDPK1ALDH1A1 | |
| SCHEMBL7942068 | 0.79 | HRH4 (0.57) | HRH4ALDH1A1HPGDAPEX1HSD17B10 | |
| SCHEMBL24113538 | 0.77 | HRH4 (0.54) | HRH4TP53POLBMAPTRXFP1 | |
| SCHEMBL25764958 | 0.77 | HRH4 (0.54) | HRH4KDM4EPDPK1ALDH1A1LMNA | |
| SCHEMBL3965725 | 0.77 | XDH (0.55) | HRH4KDM4EALDH1A1LMNAHPGD | |
| SCHEMBL16571303 | 0.77 | GRM2 (0.42) | KDM4EPDPK1ALDH1A1LMNAHPGD | |
| SCHEMBL4218397 | 0.76 | HRH4 (0.37) | HRH4MAP2K1KDM4EPDPK1ALDH1A1 | |
| SCHEMBL29990795 | 0.75 | EIF4A3 (0.48) | HRH4MAP2K1KDM4EPDPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008099165-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2008-08-21 | — | — | WO | claimed |