Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 1/20 | 0.35 |
| ▸ | MAP2 | P11137 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22395050 | 0.84 | EIF4A3 (0.65) | EIF4A3ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29425105 | 0.84 | EIF4A3 (0.65) | EIF4A3ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29062816 | 0.83 | MAP2K1 (0.43) | EIF4A3ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29063065 | 0.83 | TNF (0.42) | EIF4A3ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL28064616 | 0.81 | HRH4 (0.40) | EIF4A3ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7942068 | 0.79 | HRH4 (0.57) | ALDH1A1HPGDHSD17B10MEN1USP2 | |
| SCHEMBL30544758 | 0.77 | IDO1 (0.41) | EIF4A3MAP2K1HRH4IDO1TDO2 | |
| SCHEMBL29063177 | 0.77 | IDO1 (0.54) | EIF4A3MAP2K1HRH4IDO1TDO2 | |
| SCHEMBL5359001 | 0.75 | ALOX15 (0.57) | EIF4A3ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL25758822 | 0.75 | ALOX15 (0.57) | EIF4A3ALDH1A1TP53POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11453676-B2 | Inhibitors of protein arginine deiminases | FORWARD THERAPEUTICS, INC. (US) | 2022-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11453676-B2 | Inhibitors of protein arginine deiminases | PADI2, PADI1, PADI4 | EIF4A3 3899/4885ALDH1A1 1830/4885HPGD 266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.