Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1630772 | 0.86 | NPC1 (0.54) | NPC1L3MBTL1LMNATRPM8MMP1 | |
| SCHEMBL1022195 | 0.86 | NPC1 (0.54) | NPC1L3MBTL1LMNATRPM8MMP1 | |
| SCHEMBL1395649 | 0.86 | NPC1 (0.54) | NPC1L3MBTL1LMNATRPM8MMP1 | |
| SCHEMBL104712 | 0.79 | NPC1 (0.48) | NPC1L3MBTL1LMNATRPM8MMP1 | |
| SCHEMBL15931520 | 0.79 | NPC1 (0.48) | NPC1L3MBTL1LMNATRPM8MMP1 | |
| SCHEMBL104713 | 0.79 | NPC1 (0.48) | NPC1L3MBTL1LMNATRPM8MMP1 | |
| SCHEMBL4016170 | 0.77 | NPC1 (0.52) | NPC1L3MBTL1LMNATRPM8MMP1 | |
| SCHEMBL1395640 | 0.77 | NPC1 (0.52) | NPC1L3MBTL1LMNATRPM8MMP1 | |
| SCHEMBL2546944 | 0.77 | NPC1 (0.47) | NPC1L3MBTL1LMNATRPM8MMP1 | |
| SCHEMBL18657110 | 0.77 | NPC1 (0.47) | NPC1L3MBTL1LMNATRPM8MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119793-A1 | PROCESS FOR THE PREPARATION OF ENTACAPONE AND INTERMEDIATES THEREOF | Esteve Química, S.A. (ES) | 2008-10-09 | — | — | WO | disclosed |