Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | BRD2 | P25440 | 1/20 | 0.53 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4787693 | 0.81 | CYP2C9 (0.39) | BRD4BRD2BRD3KDM4EMAPT | |
| SCHEMBL4788324 | 0.78 | BRD4 (0.49) | BRD4BRD2BRD3KDM4EMAPT | |
| SCHEMBL7892625 | 0.78 | BRD4 (0.49) | BRD4BRD2BRD3KDM4EMAPT | |
| SCHEMBL15120570 | 0.70 | KMT2A (0.81) | BRD4BRD2BRD3ALDH1A1MAPK1 | |
| SCHEMBL11919283 | 0.70 | ALDH1A1 (0.68) | BRD4BRD2BRD3ALDH1A1MAPK1 | |
| SCHEMBL23847020 | 0.69 | ALDH1A1 (0.63) | BRD4BRD2BRD3KDM4EALDH1A1 | |
| SCHEMBL15052436 | 0.69 | GAA (0.77) | BRD4BRD2BRD3KDM4EALDH1A1 | |
| SCHEMBL1150847 | 0.69 | TSHR (0.75) | BRD4BRD2BRD3KDM4EMAPT | |
| SCHEMBL30511773 | 0.69 | ALDH1A1 (0.63) | BRD4BRD2BRD3KDM4EALDH1A1 | |
| SCHEMBL30511774 | 0.69 | ALDH1A1 (0.63) | BRD4BRD2BRD3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110891-A2 | NEW HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED, (IN) | 2008-09-18 | — | — | WO | claimed |