Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 11/20 | 0.36 |
| ▸ | BRAF | P15056 | 7/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3681771 | 0.86 | PRKD1 (0.41) | PRKD1 | |
| Trifluoroacetic Acid SCHEMBL4787685 | 0.85 | RAF1 (0.36) | RAF1BRAFPRKD1TP53MAPT | |
| Trifluoroacetic Acid SCHEMBL3681763 | 0.72 | PRKD1 (0.42) | PRKD1 | |
| Trifluoroacetic Acid SCHEMBL3681768 | 0.71 | PRKD1 (0.41) | PRKD1 | |
| SCHEMBL13409967 | 0.69 | PRKD1 (0.43) | PRKD1 | |
| SCHEMBL3690064 | 0.67 | HDAC3 (0.39) | MAPT | |
| SCHEMBL8352356 | 0.66 | PLK1 (0.42) | MAPTCDK8 | |
| SCHEMBL13993995 | 0.63 | KDM4E (0.35) | RAF1BRAFTP53MAPTCDK8 | |
| SCHEMBL3679511 | 0.63 | CTSG (0.42) | — | |
| SCHEMBL3680889 | 0.62 | ALDH1A1 (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | claimed |