Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 9/20 | 0.72 |
| ▸ | UBA2 | Q9UBT2 | 9/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.68 |
| ▸ | CASP1 | P29466 | 8/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.68 |
| ▸ | BLM | P54132 | 7/20 | 0.68 |
| ▸ | NSD2 | O96028 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.68 |
| ▸ | RECQL | P46063 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.68 |
| ▸ | CASP6 | P55212 | 2/20 | 0.68 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.68 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15032605 | 0.97 | SAE1 (0.76) | SAE1UBA2KDM4ECASP1HSD17B10 | |
| SCHEMBL4787894 | 0.91 | KDM4E (0.68) | SAE1UBA2KDM4ECASP1HSD17B10 | |
| SCHEMBL15256874 | 0.84 | SAE1 (1.00) | SAE1UBA2KDM4ECASP1HSD17B10 | |
| SCHEMBL8147117 | 0.84 | KDM4E (0.75) | SAE1UBA2KDM4ECASP1HSD17B10 | |
| SCHEMBL4787299 | 0.81 | KDM4E (0.72) | SAE1UBA2KDM4ECASP1HSD17B10 | |
| SCHEMBL4787869 | 0.81 | SAE1 (1.00) | SAE1UBA2KDM4ECASP1HSD17B10 | |
| SCHEMBL4787907 | 0.81 | SAE1 (0.94) | SAE1UBA2KDM4ECASP1HSD17B10 | |
| SCHEMBL15256907 | 0.80 | SAE1 (1.00) | SAE1UBA2KDM4ECASP1HSD17B10 | |
| SCHEMBL15256873 | 0.79 | SAE1 (0.87) | SAE1UBA2KDM4ECASP1HSD17B10 | |
| SCHEMBL4787545 | 0.78 | SAE1 (1.00) | SAE1UBA2KDM4ECASP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073941-B2 | Compounds and methods for treating tuberculosis infection | ACADEMIA SINICA (TW) | 2015-07-07 | — | — | US | disclosed |
| US-9073941-B2 | Compounds and methods for treating tuberculosis infection | ACADEMIA SINICA (TW) | 2015-07-07 | — | — | US | disclosed |
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-06-20 | — | — | US | disclosed |
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | ACADEMIA SINICA (TW) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158037-A1 | COMPOUNDS AND METHODS FOR TREATING TUBERCULOSIS INFECTION | TALDO1, PGD, DLD | SAE1 2017/4885UBA2 2986/4885KDM4E 903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.