Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 17/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14099977 | 0.87 | ADRB2 (0.54) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL4787942 | 0.81 | ADRB2 (0.49) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL4787937 | 0.78 | ADRB2 (0.49) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL8674037 | 0.76 | ADRB2 (0.55) | ADRB2ADRB1DRD2 | |
| SCHEMBL4739379 | 0.74 | ADRB2 (0.53) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL27717348 | 0.72 | ADRB2 (0.59) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL27738410 | 0.71 | ADRB2 (0.58) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL4443114 | 0.70 | ADRB2 (0.68) | ADRB2ABCB11 | |
| SCHEMBL4440137 | 0.70 | ADRB2 (0.56) | ADRB2ABCB11ADRB1DRD2PDE4A | |
| SCHEMBL7838985 | 0.70 | ADRB2 (0.67) | ADRB2ABCB11ADRB1DRD2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149110-A1 | BICYCLOR [2.2.1] HEPT-7-YLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASES AND CONDITIONS IN WHICH M3 MUSCARINIC RECEPTOR ACTIVITY AND BETA-ADRENERGIC ACTIVITY ARE IMPLICATED | ARGENTA DISCOVERY LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008096127-A2 | BICYCLO[2.2.1]HEPT-7-YLAMINE DERIVATIVES AND THEIR USE AS M3 MUSCARINIC RECEPTOR MODULATORS | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |