Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739379 | 0.86 | ADRB2 (0.53) | ADRB2ADRB1DRD2 | |
| SCHEMBL9522342 | 0.85 | ADRB2 (0.72) | ADRB2ADRB1DRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL8882013 | 0.84 | ADRB2 (0.71) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL9520760 | 0.82 | ADRB2 (0.66) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL14099977 | 0.82 | ADRB2 (0.54) | ADRB2ADRB1DRD2ADRA1D | |
| Hydrochloric Acid SCHEMBL8881126 | 0.82 | ADRB2 (0.65) | ADRB2ADRB1DRD2ADRA1D | |
| SCHEMBL4440137 | 0.78 | ADRB2 (0.56) | ADRB2ADRB1DRD2 | |
| SCHEMBL4787938 | 0.76 | ADRB2 (0.49) | ADRB2ADRB1DRD2 | |
| SCHEMBL3685868 | 0.75 | ADRB2 (0.49) | ADRB2ADRB1DRD2 | |
| SCHEMBL14077127 | 0.75 | ADRB2 (0.56) | ADRB2ADRB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763465-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| US-5648370-A | 7-(2-aminoethyl) benzothiazolones | ASTRA PHARMACEUTICALS LIMITED (GB) | 1997-07-15 | — | — | US | disclosed |
| WO-1992008708-A1 | BIOLOGICALLY ACTIVE AMINES | FISONS PLC (GB) | 1992-05-29 | — | — | WO | disclosed |