Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.55 |
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MYOC | Q99972 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.50 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232078 | 0.96 | KMT2A (0.55) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL4237099 | 0.91 | KMT2A (0.50) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL4238711 | 0.89 | MEN1 (0.48) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL4233910 | 0.88 | MEN1 (0.54) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL4233889 | 0.88 | KMT2A (0.52) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL4235514 | 0.88 | MEN1 (0.56) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL4233557 | 0.88 | MEN1 (0.60) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL4786973 | 0.88 | HSPB1 (0.52) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL4242559 | 0.87 | PKM (0.49) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL4786545 | 0.87 | MEN1 (0.50) | KMT2AMEN1MAPTMAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |