Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | TLR3 | O15455 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15255527 | 1.00 | S1PR1 (0.43) | S1PR1TLR3HTTMAPTNPC1 | |
| SCHEMBL15255529 | 1.00 | S1PR1 (0.43) | S1PR1TLR3HTTMAPTNPC1 | |
| SCHEMBL10102222 | 0.90 | S1PR1 (0.44) | S1PR1TLR3HTTMAPTNPC1 | |
| SCHEMBL10102217 | 0.90 | S1PR1 (0.44) | S1PR1TLR3HTTMAPTNPC1 | |
| SCHEMBL4788191 | 0.89 | HSP90AA1 (0.44) | S1PR1TLR3HTTMAPTNPC1 | |
| SCHEMBL15255524 | 0.82 | ALDH1A1 (0.34) | HTTALDH1A1LMNA | |
| SCHEMBL15255528 | 0.82 | ALDH1A1 (0.34) | HTTALDH1A1LMNA | |
| SCHEMBL10101780 | 0.78 | POLB (0.34) | S1PR1MAPTL3MBTL1 | |
| SCHEMBL10101781 | 0.78 | POLB (0.34) | S1PR1MAPTL3MBTL1 | |
| SCHEMBL660122 | 0.78 | HTT (0.43) | HTTMAPTNPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8536157-B2 | Non-steroidal compounds | THE UNIVERSITY OF MELBOURNE (AU) | 2013-09-17 | — | — | US | disclosed |
| WO-2008124878-A1 | NON-STEROIDAL COMPOUNDS | CRYPTOPHARMA PTY LTD (AU) | 2008-10-23 | — | — | WO | disclosed |