Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 5/20 | 0.53 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10298167 | 0.82 | KCNA5 (0.54) | KCNA5KCNN4MAPTMEN1KMT2A | |
| SCHEMBL14311021 | 0.81 | MAPT (0.48) | KCNA5KCNN4MAPTMEN1KMT2A | |
| SCHEMBL14304756 | 0.76 | KCNA5 (0.49) | KCNA5KCNN4MAPTMEN1KMT2A | |
| SCHEMBL13656902 | 0.74 | NPSR1 (0.59) | KCNA5KCNN4MAPTMEN1KMT2A | |
| SCHEMBL13043289 | 0.74 | NPSR1 (0.50) | KCNA5MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL14304254 | 0.73 | KCNA5 (0.49) | KCNA5KCNN4MAPTMEN1KMT2A | |
| SCHEMBL525867 | 0.73 | MAPT (0.48) | KCNA5MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL8862371 | 0.72 | NPSR1 (0.51) | KCNA5KCNN4MAPTMEN1KMT2A | |
| SCHEMBL22756280 | 0.70 | CA2 (0.48) | KCNA5MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL14288550 | 0.68 | MEN1 (0.47) | KCNA5MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109613-A1 | BENZO[C][2,7]NAPHTHYRIDINE DERIVATIVES, AND THEIR USE AS KINASE INHIBITORS | WYETH (US) | 2008-09-12 | — | — | WO | disclosed |