SCHEMBL4788568

SCHEMBL4788568

C=C[Si](C)(c1ccccc1)C1CCCCO1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 2/20 0.33
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2231439 0.83 SMN1; SMN2 (0.32) SLC6A3GAASMN1; SMN2ALDH1A1LMNA
SCHEMBL3012601 0.83 SMN1; SMN2 (0.32) SLC6A3GAASMN1; SMN2ALDH1A1LMNA
SCHEMBL2233581 0.80 SLC6A3 (0.38) SLC6A3GAASMN1; SMN2ALDH1A1LMNA
SCHEMBL629741 0.78 SLC6A3 (0.37) SLC6A3GAASMN1; SMN2ALDH1A1LMNA
SCHEMBL913098 0.76 SMN1; SMN2 (0.36) SLC6A3GAASMN1; SMN2ALDH1A1LMNA
SCHEMBL11401674 0.76 SLC6A3 (0.38) SLC6A3GAASMN1; SMN2ALDH1A1LMNA
SCHEMBL28857357 0.76 SLC6A3 (0.38) SLC6A3GAASMN1; SMN2ALDH1A1LMNA
SCHEMBL252656 0.75 SMN1; SMN2 (0.35) SLC6A3GAASMN1; SMN2ALDH1A1LMNA
SCHEMBL28814281 0.73 SLC6A3 (0.36) SLC6A3GAASMN1; SMN2ALDH1A1LMNA
SCHEMBL11560250 0.73 SMN1; SMN2 (0.34) SLC6A3GAASMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1210133-A1 HIGH REFRACTIVE INDEX SILICONE FOR USE IN INTRAOCULAR LENSES Medennium, Inc. (US) 2002-06-05 EP claimed
WO-2001017570-A1 HIGH REFRACTIVE INDEX SILICONE FOR USE IN INTRAOCULAR LENSES MEDENNIUM, INC. (US) 2001-03-15 WO claimed
CN-117903574-A PET high-toughness cold-resistant agent and preparation method thereof 东莞市锦源高分子科技有限公司 2024-04-19 CN disclosed
WO-2023076140-A1 FILLED SILICONE FOAM LAYER, COMPOSITIONS AND METHODS FOR THEIR MANUFACTURE, AND ARTICLES INCLUDING THE FILLED SILICONE FOAM LAYER ROGERS CORPORATION (US) 2023-05-04 WO disclosed
CN-110831948-B Method for preparing platinum organosiloxane complexes using ketene additives 美国陶氏有机硅公司 2022-08-23 CN disclosed
CN-114729191-A Method and apparatus components useful for producing molded silicone rubber products from liquid silicone rubber compositions via injection molding 埃肯有机硅美国公司 2022-07-08 CN disclosed
EP-3655415-B1 PROCESS FOR PREPARING PLATINUM ORGANOSILOXANE COMPLEXES USING AN ENONE ADDITIVE DOW SILICONES CORP (US) 2021-06-16 EP disclosed
EP-3655416-B1 PROCESS FOR PREPARING PLATINUM ORGANOSILOXANE COMPLEXES DOW SILICONES CORP (US) 2021-06-09 EP disclosed
US-10787474-B2 Process for preparing platinum organosiloxane complexes DOW SILICONES CORPORATION (US) 2020-09-29 US disclosed
US-10723843-B2 Process for preparing platinum organosiloxane complexes using an enone additive DOW SILICONES CORPORATION (US) 2020-07-28 US disclosed
US-20200181183-A1 PROCESS FOR PREPARING PLATINUM ORGANOSILOXANE COMPLEXES DOW SILICONES CORP (US) 2020-06-11 US disclosed
WO-2008124810-A1 FOAM ARTICLES AND METHODS OF PRODUCING THE SAME WORLD PROPERTIES, INC. (US) 2008-10-16 WO disclosed
WO-2005012435-A1 ELECTRICALLY CONDUCTIVE, FLAME RETARDANT FILLERS, METHOD OF MANUFACTURE, AND USE THEREOF WORLD PROPERTIES, INC. (US) 2005-02-10 WO disclosed
WO-2003085681-A1 ELECTRICALLY CONDUCTIVE POLYMERIC FOAMS AND ELASTOMERS AND METHODS OF MANUFACTURE THEREOF WORLD PROPERTIES, INC. (US) 2003-10-16 WO disclosed
EP-1212380-A1 CHEMICALLY MODIFIED SILICA FILLERS, PROCESS FOR PRODUCING, AND SILICONE COMPOSITIONS CONTAINING SAME DOW CORNING CORPORATION (US) 2002-06-12 EP disclosed
US-6384125-B1 CONTACTING ACIDIC AQUEOUS SUSPENSION OF PRECIPITATED OR COLLOIDAL SILICA WITH COMBINATION OF FUNCTIONALIZING COUPLING AGENT AND ORGANOMETALLIC HYDROPHOBING COMPOUND, NEUTRALIZING TO INCREASE PH, RECOVERING MODIFIED FILLER DOW CORNING CORPORATION 2002-05-07 US disclosed
WO-2001014480-A1 CHEMICALLY MODIFIED SILICA FILLERS, PROCESS FOR PRODUCING, AND SILICONE COMPOSITIONS CONTAINING SAME DOW CORNING CORPORATION (US) 2001-03-01 WO disclosed
US-5990223-A DETERMINING THE VOLUME FRACTION BY A REGRESSION ANALYSIS EQUATION RELATING THE VOLUME FRACTION, CARMAN SURFACE AREA (CSA), AND BURNAUER-EMMET-TELLER SURFACE AREA (BET) OF THE REINFORCING SILICA FILLER TO THE DESIRED PROPERTY DOW CORNING CORPORATION (US) 1999-11-23 US disclosed
EP-0936241-A1 Control of rheological and mechanical properties of silicone elastomers containing silica filler DOW CORNING CORPORATION (US) 1999-08-18 EP disclosed
US-3978025-A COATINGS FOR ELECTRICAL CONDUCTORS RHONE-POULENC S.A. (FR) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10787474-B2 Process for preparing platinum organosiloxane complexes H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DHPS, PCBP1 SLC6A3 4248/4885GAA 3283/4885SMN1; SMN2 2781/4885
US-20200181183-A1 PROCESS FOR PREPARING PLATINUM ORGANOSILOXANE COMPLEXES H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DHPS, PCBP1 SLC6A3 4248/4885GAA 3283/4885SMN1; SMN2 2781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.