SCHEMBL4788577

SCHEMBL4788577

CCCCC(CCCC)NCCCNC(CCCC)CCCC

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.38
EPHX1 P07099 1/20 0.38
ALDH1A1 P00352 4/20 0.37
TSHR P16473 3/20 0.37
CYP3A4 P08684 1/20 0.37
SIGMAR1 Q99720 1/20 0.35
LMNA P02545 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
CNR1 P21554 1/20 0.35
ADRA1A P35348 1/20 0.35
KDM4E B2RXH2 1/20 0.35
PLA2G2C Q5R387 2/20 0.33
DPP7 Q9UHL4 1/20 0.33
ABCC3 O15438 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11897245 0.92 EPHX1 (0.48) DNM1EPHX1ALDH1A1TSHRCYP3A4
SCHEMBL29107027 0.90 EPHX1 (0.52) DNM1EPHX1ALDH1A1TSHRSIGMAR1
SCHEMBL11897242 0.90 EPHX1 (0.52) DNM1EPHX1ALDH1A1TSHRSIGMAR1
SCHEMBL20798577 0.90 DNM1 (0.40) DNM1EPHX1ALDH1A1TSHRCYP3A4
SCHEMBL4719013 0.90 SIGMAR1 (0.41) DNM1EPHX1ALDH1A1TSHRCYP3A4
SCHEMBL5371278 0.89 DNM1 (0.43) DNM1EPHX1ALDH1A1TSHRCYP3A4
Hydrochloric Acid SCHEMBL27765502 0.87 EPHX1 (0.50) DNM1EPHX1ALDH1A1TSHRPLA2G2C
SCHEMBL28177813 0.87 EPHX1 (0.44) DNM1EPHX1ALDH1A1TSHRLMNA
SCHEMBL9203670 0.87 EPHX1 (0.50) DNM1EPHX1ALDH1A1TSHRLMNA
SCHEMBL25971689 0.87 EPHX1 (0.50) DNM1EPHX1ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008130721-A1 PREPARATION OF SECONDARY DIAMINES ALBEMARLE CORPORATION (US) 2008-10-30 WO disclosed