Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.57 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744698 | 0.79 | FFAR1 (0.63) | FFAR1PPARAPPARG | |
| SCHEMBL16555730 | 0.78 | TSHR (0.54) | HTR2BHTR2CTSHRELANEHDAC1 | |
| SCHEMBL4745030 | 0.77 | PPARG (0.59) | FFAR1PPARAPPARG | |
| SCHEMBL693351 | 0.76 | TSHR (0.63) | HTR2BHTR2CTSHRELANE | |
| SCHEMBL4069956 | 0.76 | TSHR (0.63) | HTR2BHTR2CTSHRELANE | |
| SCHEMBL630517 | 0.76 | TSHR (0.63) | HTR2BHTR2CTSHRELANE | |
| Hydrochloric Acid SCHEMBL1000787 | 0.75 | TSHR (0.65) | HTR2BHTR2CTSHRELANE | |
| Hydrochloric Acid SCHEMBL693350 | 0.75 | TSHR (0.65) | HTR2BHTR2CTSHRELANE | |
| Hydrochloric Acid SCHEMBL630516 | 0.75 | TSHR (0.65) | HTR2BHTR2CTSHRELANE | |
| SCHEMBL4744629 | 0.74 | KDR (0.62) | FFAR1PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117982-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR INHIBITING LIPID ACCUMULATION CONTAINING SAME | CRYSTAL GENOMICS, INC. (KR) | 2008-10-02 | — | — | WO | disclosed |