Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.82 |
| ▸ | NPC1 | O15118 | 5/20 | 0.82 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.77 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.76 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.72 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.70 |
| ▸ | PLAU | P00749 | 1/20 | 0.69 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.68 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | GSK3B | P49841 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30341896 | 0.94 | RAB9A (0.89) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL2919439 | 0.90 | RAB9A (0.87) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL4963650 | 0.90 | RAB9A (1.00) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| Iodide SCHEMBL30758596 | 0.89 | RAB9A (0.97) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL29693066 | 0.89 | RAB9A (0.97) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL6799157 | 0.88 | RAB9A (1.00) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL19500980 | 0.88 | RAB9A (0.82) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL12010917 | 0.88 | RAB9A (0.82) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL5340339 | 0.88 | RAB9A (0.88) | RAB9ANPC1TP53ALOX15SMN1; SMN2 | |
| SCHEMBL11548282 | 0.86 | RAB9A (0.90) | RAB9ANPC1TP53ALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954670-A2 | NUCLEAR RECEPTOR BINDING AGENTS | GTX Inc. (US) | 2008-08-13 | — | — | EP | claimed |
| WO-2007062230-A2 | NUCLEAR RECEPTOR BINDING AGENTS | GTX, INC. (US) | 2007-05-31 | — | — | WO | claimed |
| WO-2008130571-A1 | NUCLEAR RECEPTOR BINDING AGENTS | GTX, INC. (US) | 2008-10-30 | — | — | WO | disclosed |