Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.51 |
| ▸ | GSK3B | P49841 | 6/20 | 0.42 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NAT1 | P18440 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | ME2 | P23368 | 1/20 | 0.34 |
| ▸ | ME1 | P48163 | 1/20 | 0.34 |
| ▸ | ME3 | Q16798 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788888 | 0.85 | PTGS2 (0.50) | PTGS2GSK3BHPGDNAT1 | |
| SCHEMBL4460171 | 0.78 | MEN1 (0.50) | PTGS2ESR2ESR1HPGDRAB9A | |
| SCHEMBL6702892 | 0.71 | PTGS2 (0.59) | PTGS2GSK3BSENP1ESR2ESR1 | |
| SCHEMBL9065257 | 0.68 | PTGS2 (0.61) | PTGS2GSK3BSENP1ESR2ESR1 | |
| SCHEMBL28862647 | 0.68 | GSK3B (0.57) | PTGS2GSK3BSENP1ESR2ESR1 | |
| SCHEMBL14026490 | 0.68 | PTGS2 (0.56) | PTGS2GSK3BSENP1ESR2ESR1 | |
| SCHEMBL28080907 | 0.67 | PTGS2 (0.72) | PTGS2GSK3BGSK3ARAB9ATDP1 | |
| SCHEMBL4752018 | 0.67 | PTGS2 (0.49) | PTGS2HPGDTDP1 | |
| SCHEMBL18049411 | 0.67 | PTGS2 (0.54) | PTGS2GSK3BSENP1ESR2ESR1 | |
| SCHEMBL22954264 | 0.66 | ESR2 (0.58) | PTGS2GSK3BESR2ESR1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140251-A2 | CYCLOOXYGENASE-2 INHIBITORS | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140251-A2 | CYCLOOXYGENASE-2 INHIBITORS | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2008-11-20 | — | — | WO | disclosed |