SCHEMBL4789153

SCHEMBL4789153

O=C1CCC2C(=CC=C3N=CC=C32)N1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 13/20 0.36
CRBN Q96SW2 13/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7099066 0.60 CRBN (0.33) DDB1CRBN
SCHEMBL248663 0.59 DDB1 (0.33) DDB1CRBN
SCHEMBL10620948 0.59 CRBN (0.42) DDB1CRBN
SCHEMBL9239478 0.57 CRBN (0.37) DDB1CRBN
SCHEMBL1995236 0.57 CRBN (0.36) DDB1CRBN
SCHEMBL6232358 0.57 CRBN (0.33) DDB1CRBN
SCHEMBL7986251 0.54 CRBN (0.33) DDB1CRBN
SCHEMBL33371399 0.54 CRBN (0.33) DDB1CRBN
SCHEMBL68773 0.54 CRBN (0.33) DDB1CRBN
SCHEMBL19586225 0.54 CRBN (1.00) DDB1CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1891067-A2 ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS, INC. (US) 2008-02-27 EP disclosed
WO-2006138347-A2 ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INCORPORATED (US) 2006-12-28 WO disclosed