SCHEMBL4789182

SCHEMBL4789182

CC(C)(C=Cc1ccccc1)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.50
MAOB P27338 2/20 0.44
CHAT P28329 2/20 0.40
EGFR P00533 1/20 0.40
MAPK1 P28482 2/20 0.39
TRPA1 O75762 2/20 0.39
RELA Q04206 1/20 0.39
GLA P06280 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 2/20 0.39
TSHR P16473 2/20 0.39
NFE2L2 Q16236 1/20 0.38
CYP19A1 P11511 1/20 0.38
MAOA P21397 1/20 0.38
LMNA P02545 1/20 0.38
ALOX5 P09917 1/20 0.38
NPC1 O15118 1/20 0.37
HDAC3 O15379 1/20 0.37
TNKS O95271 1/20 0.37
HDAC4 P56524 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6546422 1.00 CYP2C19 (0.50) CYP2C19MAOBCHATEGFRMAPK1
SCHEMBL3068732 0.83 TRPA1 (0.61) CYP2C19MAOBTRPA1RELAALDH1A1
SCHEMBL28706854 0.82 CYP2C19 (0.50) CYP2C19MAOBCHATEGFRMAPK1
SCHEMBL9906171 0.78 CYP2C19 (0.52) CYP2C19MAOBCHATEGFRGLA
SCHEMBL15689522 0.78 CYP2C19 (0.52) CYP2C19MAOBCHATEGFRGLA
SCHEMBL6286942 0.78 CYP2C19 (0.55) CYP2C19MAOBCHATEGFRMAPK1
SCHEMBL28939716 0.78 CYP2C19 (0.55) CYP2C19MAOBCHATEGFRMAPK1
SCHEMBL3259240 0.78 CYP2C19 (0.55) CYP2C19MAOBCHATEGFRMAPK1
SCHEMBL26917 0.78 CYP2C19 (0.55) CYP2C19MAOBCHATEGFRMAPK1
SCHEMBL24188664 0.77 CYP2C19 (0.46) CYP2C19MAOBCHATEGFRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008123387-A2 WATER-BASED PAINT COMPOSITIONS AND MULTILAYER COATING FILM FORMING METHOD KANSAI PAINT CO., LTD. (JP) 2008-10-16 WO disclosed
EP-0717098-B1 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON MITSUBISHI OIL CORP (JP) 2004-01-21 EP disclosed
US-5817251-A AROMATIC HYDROCARBON LUBRICANT NIPPON OIL CO., LTD. (JP) 1998-10-06 US disclosed
US-5711895-A Fluid composition for use in a refrigerating machine in which the refrigerating machine oil is at least one hydrocarbon compound of a formula consisting of two phenyl groups joined through an alkylene or alkenylene group NIPPON OIL CO., LTD. (JP) 1998-01-27 US disclosed
EP-0717098-A2 A refrigerating machine oil and a fluid composition for use in a refrigerating machine NIPPON OIL CO. LTD. (JP) 1996-06-19 EP disclosed