Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752838 | 0.69 | MAPT (0.79) | MEN1KMT2AAPOBEC3GMAPTKDM4E | |
| SCHEMBL14060010 | 0.62 | LMNA (0.49) | MEN1KMT2AAPOBEC3GMAPTHPGD | |
| SCHEMBL27768193 | 0.62 | POLB (0.45) | MEN1KMT2AAPOBEC3GMAPTHPGD | |
| SCHEMBL5435914 | 0.62 | MEN1 (1.00) | MEN1KMT2AAPOBEC3GMAPTHPGD | |
| SCHEMBL30846491 | 0.62 | KMT2A (0.57) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL28688757 | 0.61 | LMNA (0.60) | KMT2AMAPTKDM4EGLATSHR | |
| SCHEMBL18292584 | 0.59 | MAPT (0.78) | MAPTKDM4EALDH1A1TDP1LMNA | |
| SCHEMBL15655454 | 0.59 | AR (0.51) | MAPTALDH1A1LMNASMN1; SMN2HSD17B10 | |
| SCHEMBL8022032 | 0.58 | NPC1 (0.65) | MEN1KMT2AMAPTALDH1A1TSHR | |
| SCHEMBL27584986 | 0.58 | NPSR1 (0.52) | MAPTHPGDKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | ELECTROPHORETICS LIMITED (GB) | 2016-12-08 | — | — | US | disclosed |
| WO-2008155054-A1 | FARNESOID-X-RECEPTOR MUTANTS, AND CRYSTALLISATION THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160354375-A1 | CASEIN KINASE 1delta (CK 1delta) INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES SUCH AS TAUOPATHIES | CSNK1G1, CSNK1A1, CSNK1D | MEN1 3510/4885KMT2A 810/4885APOBEC3G 3875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.