Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6599925 | 0.79 | KMT2A (0.42) | RAB9AMEN1KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL1194570 | 0.78 | KMT2A (0.41) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL28114539 | 0.77 | RAB9A (0.53) | POLBRAB9AMAPTTDP1LMNA | |
| SCHEMBL27927550 | 0.76 | TDP1 (0.43) | MEN1KMT2AAPOBEC3GMAPTTDP1 | |
| SCHEMBL4495822 | 0.73 | ADRA1D (0.45) | POLBMEN1KMT2AAPOBEC3GHIF1A | |
| SCHEMBL5113969 | 0.72 | RAB9A (0.52) | POLBRAB9AMEN1KMT2AMAPT | |
| SCHEMBL18586692 | 0.72 | RAB9A (0.55) | POLBRAB9AKMT2AMAPTTDP1 | |
| SCHEMBL20542272 | 0.72 | RAB9A (0.55) | POLBRAB9AMEN1KMT2AMAPT | |
| SCHEMBL31559974 | 0.72 | RAB9A (0.55) | POLBRAB9AKMT2AMAPTTDP1 | |
| SCHEMBL14644365 | 0.72 | RAB9A (0.55) | POLBRAB9AKMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100572381-C | Pyrazolonaphthyridine derivative | ASKA PHARM CO LTD (JP) | 2009-12-23 | — | — | CN | disclosed |