Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31119754 | 0.83 | IKBKB (0.56) | MAPTMAPK1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12157404 | 0.75 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3756445 | 0.74 | KDM4E (0.45) | MAPTMAPK1L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL5375181 | 0.73 | MAPT (0.46) | MAPTMAPK1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1144922 | 0.71 | NPC1 (0.53) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL742714 | 0.71 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL4238576 | 0.71 | RXFP1 (0.60) | CA12CA9L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL22955425 | 0.71 | RIPK1 (0.62) | L3MBTL1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22952463 | 0.71 | ALDH1A1 (0.50) | MAPTL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL13211046 | 0.71 | ALDH1A1 (0.60) | L3MBTL1ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879877-A2 | ANTIMICROBIAL AGENTS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117762-A2 | ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |