Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6649442 | 0.77 | TSHR (0.42) | TSHRL3MBTL1TDP1PPARGMAPK1 | |
| SCHEMBL31536390 | 0.73 | TSHR (0.43) | TSHRL3MBTL1TDP1PPARGMAPK1 | |
| SCHEMBL700153 | 0.72 | TSHR (0.55) | TSHRL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL3588372 | 0.70 | ALDH1A1 (0.42) | TSHRTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL7370924 | 0.69 | PPARG (0.42) | TSHRL3MBTL1TDP1PPARGMAPK1 | |
| SCHEMBL13610184 | 0.69 | CHRM2 (0.47) | TSHRPPARGMAPK1CYP3A4TP53 | |
| SCHEMBL11341175 | 0.69 | TSHR (0.39) | TSHRL3MBTL1TDP1PPARGMAPK1 | |
| SCHEMBL27492109 | 0.69 | GAA (0.54) | TSHRL3MBTL1TDP1PPARGMAPK1 | |
| SCHEMBL877398 | 0.68 | TSHR (0.53) | TSHRL3MBTL1TDP1PPARGMAPK1 | |
| SCHEMBL13610179 | 0.68 | CHRM2 (0.46) | TSHRPPARGMAPK1CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141385-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2008-11-27 | — | — | WO | disclosed |