Tetrahydrofuran

Tetrahydrofuran

SCHEMBL479

C1CCOC1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL6364293 1.00 ALDH1A1 (1.00)
Tetrahydrofuran SCHEMBL6298732 1.00
Tetrahydrofuran SCHEMBL378197 1.00 ALDH1A1 (1.00)
SCHEMBL30432886 1.00 ALDH1A1 (1.00)
SCHEMBL3455441 1.00 ALDH1A1 (1.00)
Tetrahydrofuran SCHEMBL1982618 1.00
SCHEMBL30466481 1.00 ALDH1A1 (1.00)
SCHEMBL9576477 1.00 ALDH1A1 (1.00)
Tetrahydrofuran SCHEMBL130914 1.00
Tetrahydrofuran SCHEMBL5125765 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 1854445 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6432596-B1 None US claimed
US-9975833-B2 Efficient catalyst for the formation of polyaryl hydrocarbons suitable as precursors for polydentate organophosphorus catalyst ligands EASTMAN CHEMICAL COMPANY (US) 2018-05-22 US claimed
US-9975823-B2 Process for the preparation of 5-bromo-1,2,3-trichlorobenzene SYNGENTA PARTICIPATIONS AG (CH) 2018-05-22 US claimed
US-9979008-B2 Methods for making a solid electrolyte interface layer on a surface of an electrode GM Global Technology Operations LLC (US) 2018-05-22 US claimed
US-9976072-B2 Multicarboxylate compositions and method of making the same CHEVRON U.S.A. INC. (US) 2018-05-22 US claimed
WO-2018089645-A1 POLYURETHANE COMPRISING GRAPHENE NANO STRUCTURE BASF SE (DE) 2018-05-17 WO claimed
US-20180134738-A1 DISUBSTITUTED ALKYNE DICOBALT HEXACARBONYL COMPOUNDS, METHOD OF MAKING AND METHOD OF USE THEREOF VERSUM MATERIALS US, LLC (US) 2018-05-17 US claimed
US-20180134656-A1 INTERMEDIATES AND METHODS FOR SYNTHESIZING CALICHEAMICIN DERIVATIVES PFIZER INC. (US) 2018-05-17 US claimed
US-20180135141-A1 CONSTITUTIVE 1,4-DIOXANE-DEGRADING BACTERIA TAISEI CORPORATION (JP) 2018-05-17 US claimed
WO-2018087561-A1 PROCESS FOR THE PREPARATION OF UMECLIDINIUM BROMIDE HOVIONE SCIENTIA LIMITED (IE) 2018-05-17 WO claimed
US-3950498-A Process for the production of sulfur tetrafluoride Appel, Rolf (DT) 1976-04-13 US claimed
US-3949006-A Synthesis of vitamin A, intermediates and conversion thereof to vitamin A SCM CORPORATION (US) 1976-04-06 US claimed
US-3947519-A Preparation of optically active allethrorone via allethronyl acid phthalate SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-03-30 US claimed
US-3947517-A Stereoselective introduction of tetracyclines hydroxyl group at 12(a) position in synthesis of tetracyclines RESEARCH CORPORATION (US) 1976-03-30 US claimed
US-3946093-A FROM HIGH PRESSURE ZONE TO LOW PRESSURE ZONE NISSAN CHEMICAL INDUSTRIES, LTD. (JA) 1976-03-23 US claimed
US-3941853-A HIGH ENERGY EXPLOSIVE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1976-03-02 US claimed
US-3935177-A Polymerisation and copolymerisation of dienes BAYER AKTIENGESELLSCHAFT (DT) 1976-01-27 US claimed
US-3933518-A CHLORINATED ALIPHATIC HYDROCARBONS, ALKYLENE GLYCOL ALKANOATE THE DOW CHEMICAL COMPANY (US) 1976-01-20 US claimed
US-3931836-A Laminated polymeric articles and process for the production thereof JOHNS-MANVILLE CORPORATION (US) 1976-01-13 US claimed
US-3931038-A ALKOXYLATED POLYOL PHOSPHATE, ZINC CHLORIDE, TANNIN, WATER NALCO CHEMICAL COMPANY (US) 1976-01-06 US claimed