Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31117992 | 0.95 | PNMT (0.48) | PNMTALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL31118093 | 0.79 | PNMT (0.38) | PNMTALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL9143488 | 0.75 | DPP4 (0.37) | ALDH1A1TAAR1MEN1KMT2AMAPK1 | |
| SCHEMBL10602994 | 0.74 | MAOA (0.50) | ALDH1A1TAAR1MEN1KMT2ASLC6A4 | |
| SCHEMBL2864890 | 0.74 | MAOA (0.50) | ALDH1A1TAAR1MEN1KMT2ASLC6A4 | |
| SCHEMBL2405185 | 0.74 | TAAR1 (0.55) | PNMTTAAR1SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL31118122 | 0.74 | TAAR1 (0.47) | ALDH1A1TAAR1MEN1KMT2ASLC6A4 | |
| SCHEMBL31118236 | 0.74 | TAAR1 (0.46) | ALDH1A1TAAR1IDO1CYP1A2CYP2D6 | |
| SCHEMBL31118109 | 0.74 | TAAR1 (0.46) | ALDH1A1TAAR1MEN1KMT2AMAPK1 | |
| SCHEMBL31118143 | 0.74 | HDAC4 (0.37) | ALDH1A1TAAR1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4037450-B2 | — | — | 2008-01-23 | — | — | JP | claimed |
| EP-0841909-A2 | USE OF ALICYCLIC DIAMINES AS IMMUNOMODULATORS | NEOVACS (FR) | 1998-05-20 | — | — | EP | claimed |
| WO-1997005859-A2 | USE OF ALICYCLIC DIAMINES AS IMMUNOMODULATORS | NEOVACS (FR) | 1997-02-20 | — | — | WO | claimed |
| WO-2007136250-A2 | A PHARMACEUTICAL COMPOSITION SUITABLE FOR THE TREATMENT OF CANCER AND METHOD OF PREPARING SAID PHARMACEUTICAL COMPOSITION | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2007-11-29 | — | — | WO | disclosed |
| EP-0841909-A2 | USE OF ALICYCLIC DIAMINES AS IMMUNOMODULATORS | NEOVACS (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005859-A2 | USE OF ALICYCLIC DIAMINES AS IMMUNOMODULATORS | NEOVACS (FR) | 1997-02-20 | — | — | WO | disclosed |