Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797782 | 0.91 | TSHR (0.66) | TSHRALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL8433421 | 0.86 | TSHR (0.59) | TSHRALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL16049266 | 0.86 | TSHR (0.59) | TSHRALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL17797867 | 0.86 | TSHR (0.59) | TSHRALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL14409194 | 0.84 | TSHR (0.79) | TSHRALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL28866385 | 0.84 | ALDH1A1 (0.55) | TSHRALDH1A1L3MBTL1NPC1RAB9A | |
| SCHEMBL14984028 | 0.84 | TSHR (0.68) | TSHRALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL29860709 | 0.84 | TSHR (0.65) | TSHRALDH1A1L3MBTL1TDP1MEN1 | |
| SCHEMBL29860961 | 0.83 | LMNA (0.61) | TSHRALDH1A1L3MBTL1NPC1RAB9A | |
| Propene SCHEMBL17797847 | 0.83 | TSHR (0.56) | TSHRALDH1A1L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008013860-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF ALPHA-AMINO ACIDS, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2008-01-31 | — | — | WO | claimed |