SCHEMBL479072

SCHEMBL479072

O=C(O)c1ccc(Cl)c(F)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.65
MAPT P10636 2/20 0.53
LMNA P02545 2/20 0.53
MAPK1 P28482 1/20 0.53
HTT P42858 1/20 0.53
RAB9A P51151 1/20 0.53
ALDH1A1 P00352 1/20 0.53
SRD5A2 P31213 1/20 0.52
KCNQ3 O43525 2/20 0.50
KCNQ2 O43526 2/20 0.50
KCNE1 P15382 2/20 0.50
KCNQ1 P51787 2/20 0.50
KCNQ5 Q9NR82 1/20 0.50
ALOX15 P16050 1/20 0.48
MRGPRX4 Q96LA9 1/20 0.46
KMO O15229 2/20 0.46
TP53 P04637 1/20 0.46
PTK2B Q14289 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
KDM4E B2RXH2 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31439010 0.98 TSHR (0.63) TSHRMAPTLMNAMAPK1HTT
Hydrochloric Acid SCHEMBL9190175 0.98 TSHR (0.63) TSHRMAPTLMNAMAPK1HTT
SCHEMBL3179802 0.84 CES2 (0.64) TSHRSRD5A2KCNQ3KCNQ2KCNE1
SCHEMBL27561994 0.84 SRD5A2 (0.53) TSHRSRD5A2KCNQ3KCNQ2KCNE1
SCHEMBL3026551 0.83 KCNQ3 (0.51) TSHRALDH1A1SRD5A2KCNQ3KCNQ2
SCHEMBL109599 0.83 TSHR (0.65) TSHRMAPTLMNAMAPK1HTT
SCHEMBL30308290 0.83 TSHR (0.65) TSHRMAPTLMNAMAPK1HTT
Hydrochloric Acid SCHEMBL7105574 0.81 TSHR (0.63) TSHRMAPTLMNAMAPK1HTT
SCHEMBL1719358 0.81 KCNQ3 (0.49) TSHRKCNQ3KCNQ2KCNE1KCNQ1
SCHEMBL2088683 0.81 KCNQ3 (0.49) TSHRSRD5A2KCNQ3KCNQ2KCNE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 515 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119285434-A Preparation method of 3-fluoro-4-chlorobenzyl bromide 上海泰坦科技股份有限公司 2025-01-10 CN claimed
EP-3551633-B1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA AS (DK) 2021-03-31 EP claimed
EP-3551633-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 EP claimed
EP-3551634-A1 SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS Leo Pharma A/S (DK) 2019-10-16 EP claimed
WO-2018108231-A1 SUBSTITUTED PYRAZOLOAZEPIN-8-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 WO claimed
WO-2018108230-A1 SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS LEO PHARMA A/S (DK) 2018-06-21 WO claimed
EP-2899185-B1 Processes for preparing linezolid UNIV INDIANA RES & TECH CORP (US) 2018-01-31 EP claimed
EP-2899185-A1 Processes for preparing linezolid Indiana University Research and Technology Corporation (US) 2015-07-29 EP claimed
CN-103025730-A Method for preparing linezolid UNIV INDIANA RES & TECH CORP 2013-04-03 CN claimed
EP-2563781-A1 PROCESSES FOR PREPARING LINEZOLID Indiana University Research and Technology Corporation (US) 2013-03-06 EP claimed
US-20130053557-A1 PROCESSES FOR PREPARING LINEZOLID INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2013-02-28 US claimed
WO-2011137222-A1 PROCESSES FOR PREPARING LINEZOLID INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2011-11-03 WO claimed
US-7205318-B2 Lactam-containing cyclic diamines and derivatives as a factor Xa inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2007-04-17 US claimed
US-20260132112-A1 COMPOUNDS CTXT PTY LTD (AU) 2026-05-14 US disclosed
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 EP disclosed
US-12559489-B2 Antagonistic small molecule compound having toll-like receptor 7/9 inhibitory function AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2026-02-24 US disclosed
EP-0478195-A1 Dihydropyridazinones, pyridazinones and related compounds as fungicides ROHM AND HAAS COMPANY (US) 1992-04-01 EP disclosed
US-5093515-A Intermediate for quinolone carboxylic acid bactericide ASAHI GLASS COMPANY LTD. (JP) 1992-03-03 US disclosed
CN-87106482-A Process for preparing benzoic acid derivatives 1988-03-30 CN disclosed
US-3953595-A Substituted benzoic acid hypolipemic agents PFIZER INC. (US) 1976-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132112-A1 COMPOUNDS STING1, IRF3, CGAS TSHR 1389/4885MAPT 2960/4885LMNA 2322/4885
US-12559489-B2 Antagonistic small molecule compound having toll-like receptor 7/9 inhibitory function TLR9, TLR7, TLR1 TSHR 334/4885MAPT 4451/4885LMNA 1483/4885
US-20130053557-A1 PROCESSES FOR PREPARING LINEZOLID CYP2C9, CYP2C19, CYP3A43 TSHR 4027/4885MAPT 3182/4885LMNA 431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.