Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19399643 | 0.90 | MAPT (0.61) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3506576 | 0.87 | PDE7A (0.66) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL2529627 | 0.86 | ALDH1A1 (0.67) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL5315872 | 0.84 | MAPT (0.67) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL4029870 | 0.84 | PDE7A (0.73) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3507438 | 0.83 | MEN1 (0.65) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8810667 | 0.83 | PDE7A (0.72) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL4030285 | 0.83 | MEN1 (0.61) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3505754 | 0.83 | MEN1 (0.61) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL3506769 | 0.82 | MAPT (0.60) | MAPTHPGDALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483366-B | Indole compound and preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2022-09-16 | — | — | CN | disclosed |
| EP-1957495-A1 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007064045-A1 | FUSED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-06-07 | — | — | WO | disclosed |