Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.67 |
| ▸ | MEN1 | O00255 | 7/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.59 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TTR | P02766 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27707836 | 0.93 | MEN1 (0.76) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10362242 | 0.88 | MEN1 (0.74) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5315876 | 0.87 | MAPT (0.73) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL13400264 | 0.86 | MEN1 (0.67) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL27713527 | 0.85 | ALDH1A1 (0.73) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL4790993 | 0.84 | MAPT (0.71) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL31120715 | 0.84 | HSPB1 (0.55) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL30668812 | 0.84 | L3MBTL1 (0.64) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL1339905 | 0.84 | L3MBTL1 (0.64) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL7813399 | 0.83 | MEN1 (0.72) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007071344-A2 | NOVEL COUPLING CONSTITUENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-06-28 | — | — | WO | disclosed |