Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 3/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL200933 | 0.86 | NPC1 (0.36) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL4759096 | 0.75 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL201552 | 0.74 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL2316778 | 0.71 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL2706693 | 0.71 | MET (0.33) | NPC1RAB9ASYKROCK2MYC | |
| SCHEMBL4894941 | 0.70 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL203165 | 0.69 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL27738132 | 0.68 | NPC1 (0.45) | NPC1RAB9AHPGDMEN1KMT2A | |
| SCHEMBL202304 | 0.64 | NPC1 (0.39) | NPC1RAB9ASMN1; SMN2MAPTPKM | |
| SCHEMBL203725 | 0.63 | NPC1 (0.50) | NPC1RAB9AMAPTROCK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996180-A1 | ANTIBACTERIAL AGENTS | Prolysis Limited (GB) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107758-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2007-09-27 | — | — | WO | disclosed |