Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4792086 | 0.87 | FKBP1A (0.45) | HRH3CYP2D6HRH1 | |
| SCHEMBL4791232 | 0.85 | HRH3 (0.44) | HRH3CYP2D6HRH1 | |
| SCHEMBL4775800 | 0.81 | FKBP1A (0.44) | HRH3CYP2D6HRH1 | |
| SCHEMBL4793933 | 0.81 | HRH3 (0.51) | HRH3CYP2D6 | |
| SCHEMBL4770320 | 0.80 | HRH3 (0.53) | HRH3CYP2D6HRH1 | |
| SCHEMBL4771920 | 0.76 | HRH3 (0.42) | HRH3CYP2D6 | |
| SCHEMBL4766025 | 0.76 | HRH3 (0.44) | HRH3CYP2D6HRH1 | |
| SCHEMBL4791239 | 0.76 | HRH3 (0.44) | HRH3CYP2D6 | |
| SCHEMBL4793168 | 0.76 | HRH3 (0.41) | HRH3CYP2D6HRH1 | |
| SCHEMBL4777033 | 0.75 | HRH3 (0.39) | HRH3CYP2D6HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1713778-B1 | BENZAZEPINE DERIVATIVES AS HISTAMINE H3 ANTAGONISTS | GLAXO GROUP LTD (GB) | 2008-01-16 | — | — | EP | claimed |