Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4791453 | 0.89 | CDC7 (0.46) | HSD17B10ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL11014635 | 0.82 | MAPK1 (0.52) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL6298250 | 0.77 | MAPK1 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL17671266 | 0.76 | MEN1 (0.38) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL5147054 | 0.74 | KCNH2 (0.53) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL257518 | 0.72 | SLC6A2 (0.49) | ALDH1A1MAPTHTTCYP1A2FGFR1 | |
| SCHEMBL27715918 | 0.72 | KCNH2 (0.55) | ALDH1A1MAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL5148162 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL15556871 | 0.71 | HSD17B10 (0.46) | HSD17B10ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8172653 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924557-A2 | CARBAZOLE DERIVATIVES | Serenex, Inc. (US) | 2008-05-28 | — | — | EP | disclosed |
| US-20070185184-A1 | Carbazole derivatives | SERENEX, INC. | 2007-08-09 | — | — | US | disclosed |
| WO-2007035620-A2 | CARBAZOLE DERIVATIVES | SERENEX, INC. (US) | 2007-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185184-A1 | Carbazole derivatives | CCNI, MKI67, CCNB3 | HSD17B10 3309/4885ALDH1A1 2098/4885MAPT 3286/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.