Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298250 | 0.89 | MAPK1 (0.46) | MAPK1ALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL4792254 | 0.82 | HSD17B10 (0.45) | MAPK1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL5432686 | 0.77 | LMNA (0.44) | MAPK1ALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL12584626 | 0.75 | MYC (0.51) | ALDH1A1L3MBTL1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL17671266 | 0.73 | MEN1 (0.38) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL11824811 | 0.73 | MAPK1 (0.59) | MAPK1ALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL12643016 | 0.73 | ALDH1A1 (0.44) | MAPK1ALDH1A1KMT2ALMNAPOLB | |
| SCHEMBL17029043 | 0.72 | PDE7A (0.42) | MAPK1ALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL17067714 | 0.71 | HSP90AA1 (0.46) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL9112610 | 0.71 | ALDH1A1 (0.51) | MAPK1ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129692-A2 | Dibenzodiazepin derivatives, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1985-01-02 | — | — | EP | disclosed |