Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 2/20 | 0.54 |
| ▸ | GABRP | O00591 | 2/20 | 0.53 |
| ▸ | GABRD | O14764 | 2/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6009595 | 0.89 | TSHR (0.61) | KDM4EMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5794647 | 0.86 | KDM4E (0.59) | KDM4EMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10642644 | 0.84 | KDM5A (0.55) | KDM4EMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6008342 | 0.84 | TSHR (0.54) | KDM4EMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10642534 | 0.83 | GABRP (0.58) | KDM4EMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2181558 | 0.83 | NR4A2 (0.55) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL30522265 | 0.83 | NR4A2 (0.55) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL31670359 | 0.83 | NR4A2 (0.55) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12500666 | 0.83 | ALDH1A1 (0.55) | KDM4EALDH1A1RAB9AKMT2ATSHR | |
| Hydrochloric Acid SCHEMBL10641678 | 0.82 | GABRP (0.57) | KDM4EMAPTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015040087-A1 | MACROPHAGE IMAGING | GE HEALTHCARE LIMITED (GB) | 2015-03-26 | — | — | WO | disclosed |
| EP-2621544-A1 | IN VIVO IMAGING METHOD FOR CANCER | GE Healthcare UK Limited (GB) | 2013-08-07 | — | — | EP | disclosed |
| EP-2618850-A1 | IN VIVO IMAGING METHOD OF MOOD DISORDERS | GE Healthcare UK Limited (GB) | 2013-07-31 | — | — | EP | disclosed |
| US-8486990-B2 | SirT inhibitors that bind to NAD | ELIXIR PHARMACEUTICALS, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| WO-2012041953-A1 | IN VIVO IMAGING METHOD FOR CANCER | GE HEALTHCARE LIMITED (GB) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012038532-A1 | IN VIVO IMAGING METHOD OF MOOD DISORDERS | GE HEALTHCARE LIMITED (GB) | 2012-03-29 | — | — | WO | disclosed |
| EP-2411362-A2 | INDOLE DERIVATIVES | GE Healthcare UK Limited (GB) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010109007-A2 | INDOLE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2010-09-30 | — | — | WO | disclosed |
| US-20060183022-A1 | Electrochemical cell | NEC TOKIN CORORATION (JP) | 2006-08-17 | — | — | US | disclosed |