Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 4/20 | 0.31 |
| ▸ | EIF4EBP1 | Q13541 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4525281 | 0.91 | PDE4A (0.35) | SLC22A12PDE4APDE4CPDE4DIDO1 | |
| SCHEMBL2185158 | 0.74 | PDE4A (0.34) | SLC22A12PDE4APDE4CPDE4DIDO1 | |
| SCHEMBL29397704 | 0.69 | PTGS1 (0.36) | SLC22A12ESR2CA1CA2 | |
| SCHEMBL28721905 | 0.69 | PTGS1 (0.36) | SLC22A12ESR2CA1CA2 | |
| SCHEMBL14999154 | 0.68 | SRC (0.39) | SLC22A12ESR2 | |
| SCHEMBL591544 | 0.68 | IDO1 (0.45) | SLC22A12IDO1 | |
| SCHEMBL632944 | 0.68 | LMNA (0.52) | SLC22A12 | |
| SCHEMBL22492353 | 0.67 | GAK (0.44) | SLC22A12IDO1ESR2 | |
| SCHEMBL371799 | 0.67 | PDGFRB (0.51) | — | |
| SCHEMBL26632797 | 0.67 | NR4A2 (0.45) | SLC22A12PDE4APDE4CPDE4DESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891078-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006125974-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |