Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793049 | 1.00 | MAPT (0.47) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL4789072 | 1.00 | MAPT (0.47) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL13566164 | 0.96 | PTGS2 (0.49) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL13564541 | 0.94 | MAPT (0.49) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL15385043 | 0.93 | TP53 (0.52) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL15385035 | 0.93 | TP53 (0.52) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL15385019 | 0.93 | TP53 (0.52) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL15385040 | 0.91 | MAPT (0.45) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL17676608 | 0.88 | MAPT (0.43) | MAPTTP53KDM4EALDH1A1HPGD | |
| SCHEMBL13566184 | 0.87 | ALOX5 (0.42) | MAPTTP53KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632261-B1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS INC (US) | 2016-07-13 | — | — | EP | disclosed |
| WO-2012058125-A1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS, INC. (US) | 2012-05-03 | — | — | WO | disclosed |