Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CENPE | Q02224 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 10/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882162 | 1.00 | CENPE (0.39) | CENPEMAP4K4MINK1S1PR1S1PR3 | |
| SCHEMBL5569744 | 0.89 | THRA (0.36) | S1PR1P2RX3 | |
| SCHEMBL14031435 | 0.87 | DHODH (0.43) | CENPEMAP4K4MINK1S1PR1S1PR3 | |
| SCHEMBL5565637 | 0.86 | CENPE (0.39) | CENPEMAP4K4MINK1S1PR1S1PR3 | |
| SCHEMBL5565628 | 0.86 | CENPE (0.39) | CENPEMAP4K4MINK1S1PR1S1PR3 | |
| SCHEMBL3462435 | 0.85 | CENPE (0.54) | CENPEMAP4K4MINK1S1PR1S1PR3 | |
| SCHEMBL13161714 | 0.85 | CENPE (0.54) | CENPEMAP4K4MINK1S1PR1S1PR3 | |
| SCHEMBL14529933 | 0.84 | S1PR1 (0.36) | CENPEMAP4K4MINK1S1PR1S1PR3 | |
| SCHEMBL5568783 | 0.83 | S1PR1 (0.34) | CENPEMAP4K4MINK1S1PR1S1PR3 | |
| SCHEMBL5568781 | 0.83 | S1PR1 (0.34) | CENPEMAP4K4MINK1S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942732-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |