Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL580930 | 0.74 | APLNR (0.32) | APLNR | |
| SCHEMBL1983555 | 0.72 | APLNR (0.31) | APLNR | |
| SCHEMBL22906 | 0.72 | APLNR (0.31) | APLNR | |
| SCHEMBL16911410 | 0.72 | APLNR (0.31) | APLNR | |
| SCHEMBL16499990 | 0.72 | APLNR (0.31) | APLNR | |
| SCHEMBL102863 | 0.72 | NCF1 (0.39) | APLNR | |
| SCHEMBL22907 | 0.72 | APLNR (0.55) | APLNR | |
| SCHEMBL178339 | 0.72 | KDM4E (0.42) | APLNR | |
| SCHEMBL3941149 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL306682 | 0.70 | NCF1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001876-A2 | 8-AZABICYCLOÝ3.2.1¨OCTANE COMPOUNDS AS MU OPIOID RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2008-12-17 | — | — | EP | disclosed |
| WO-2007103187-A2 | 8-AZABICYCLO[3.2.1]OCTANE COMPOUNDS AS MU OPIOID RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2007-09-13 | — | — | WO | disclosed |